High-Purity Tobacco Product Ingredient – FDA TPMF Established
Maoming Teanhee Biotechnology Co., Ltd. is pleased to offer Nicotine Ditartrate Dihydrate, a pharmaceutically-grade nicotine salt designed for use in modern tobacco product development. This stable, non-hygroscopic crystalline form combines nicotine with L-tartaric acid in a precise 1:2 molar ratio, delivering enhanced solubility and improved stability compared to freebase nicotine.
Our Nicotine Ditartrate Dihydrate is manufactured under strict quality controls and has been accepted by the U.S. Food and Drug Administration (FDA) Center for Tobacco Products as a Tobacco Product Master File (TPMF), assigned FDA Submission Tracking Number MF0001525 (established May 28, 2026). This TPMF is available for reference by third parties to support their FDA submissions, such as Premarket Tobacco Product Applications (PMTAs).
Key Features:
Chemical name: Nicotine Ditartrate Dihydrate
CAS No.: 6019-06-3 (dihydrate form)
Purity: ≥99.0% (by HPLC)
Appearance: White to off-white crystalline powder
Solubility: Freely soluble in water
Stability: Excellent under recommended storage conditions
Applications:
Tobacco product research and development
E-liquid formulations for electronic nicotine delivery systems (ENDS)
Nicotine replacement therapy (NRT) product development (where permitted)
